No standard per-phage count
Multi-phage cocktails are dosed without an independent, absolute count of each phage in the mix.
Standardized measurement for phage therapy
Count every phage. Verify every dose.
Veriphage is a San Diego ddPCR lab building the standardized measurement assays phage therapy still lacks — per-phage cocktail quantification, in-vivo PK, and resistance & neutralization readouts.
The gap
Phage trials still fly blind on their own dose.
PhagoBurn — the field's marquee randomized trial — couldn't quantify how much of each phage was in its cocktail. Years later, the gap is still open. Regulators are beginning to ask for data the field can't yet produce.
No routine in-vivo PK
There's no standard assay for how much phage is actually circulating across timepoints.
No standard neutralization readout
Anti-phage immunity goes unmeasured — so trials get dinged for readouts they never ran.
PhageMetric · what we measure
ddPCR-native contract assays — standardized and reportable.
You supply the assay, or we develop it as a separate method-development project. Endotoxin and WGS available through vetted partners.
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01
Per-phage cocktail quantification
Count each phage in a multi-phage product independently — for CMC lot release and dose verification. The named PhagoBurn gap.
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02
In-vivo phage PK
Absolute phage-genome copies in plasma, sputum, or tissue across timepoints.
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03
Productive replication vs. binding
Confirm phage are actually killing their host — not just attaching to it.
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04
Resistance & heteroresistance
Quantify rare resistance alleles and heteroresistant subpopulations — where digital partitioning shines.
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05
Serum neutralization & immunogenicity
Measure anti-phage neutralization — the readout immune-monitoring needs.
Why Veriphage
Absolute counting, at a cost structure CROs can't match.
Digital partitioning gives absolute molecule counts and rare-event sensitivity — the right tool for per-phage quantification and resistance detection.
Founded by a Bio-Rad field service engineer who services the instrument fleet in-house — so our cost structure isn't a generic CRO's.
GLP-style methods and clean, reportable results your regulatory package can stand on.
About 20 minutes from UCSD. Fast turnaround, and you talk to the person running your samples.
How a pilot works
Pilot us on one cocktail.
01
Send one cocktail
Ship us a single multi-phage product, or a set of samples from one study.
02
We quantify each phage
Independent, absolute counts per phage, on a validated method.
03
You get a reportable number
A standardized report you can act on. If it's useful, we run your pipeline.
Let's measure your phages.
Tell us about one cocktail or one study. We'll tell you exactly what we can quantify — and what it costs.
Start a pilot